Product Details
Product Details
Product Specification
Synonym | Adipogenesis inhibitory factor; AGIF; AGIFoprelvekin; IL11; IL-11; IL-11Oprelvekin; interleukin 11; interleukin-11; Oprelvekin |
Description |
Testing Principle:
Detection type:Double sandwich enzyme immunoassay Form: pre-coated 96-well plate Sample type: Cell culture supernatant, Serum, Plasma Sample quantity:100 μl Kit composition:pre-coated 96-well plate,Standards,IL-11 test antibody, Standard Diluent, Test Buffer, TMB Color Substrate, Washing Solution, Stop Solution, SA-HRP, Seal Plate Mask, and Instructions . Sensitivity:5.01 pg/mL Detection range:62.5-4000 pg/mL Recovery rate: 84-118% Storage:2-8℃ The standard curve: Background: Interleukin 11 (IL-11) is a pluripotent cytokine that was isolated from bone marrow mesenchymal stem cells as early as 1990. It is a member of the IL-6 cytokine family and can be distinguished according to the co-receptor they use, gp130. IL-11 plays an important regulatory role in hematopoietic regulation, especially in stimulating the maturation of megakaryocytes. Studies have shown that IL-11 can improve chemotherapy-induced laminopenia, induce acute phase protein, regulate antigen-antibody response, and participate in the regulation of proliferation and differentiation of bone cells. IL-11 causes bone resorption and also stimulates the growth of certain lymphocytes and, in a mouse model, increases the thickness and strength of the long bone cortex. As a signaling molecule, IL-11 has a variety of functions, including placental formation and to some extent decidualization, and plays a role in the implantation of blastocysts into the endometrium. IL-11, which is made using recombinant DNA technology and is marketed as Oprexil interleukin, is used to prevent severe thrombocytopenia in cancer patients. |
