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Amyloid beta Recombinant Rabbit mAb Kit

Amyloid beta Recombinant Rabbit mAb Kit

Catalog Number: S0B3392
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Regular price $78.00 SGD
Regular price Sale price $78.00 SGD
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Product Details

Components

Catalog Number Commodity&Descriptions (Reagent/Antibodies) Pack Size (ML/MG/UG) Quantity (KIT/Bottle/PIECE)
SOB3392 Amyloid beta 1 - 40 Recombinant Rabbit mAb (SDT - 1548 - 52) 0.2mg 1 pc
SOB3393 Amyloid beta 1 - 40 Recombinant Rabbit mAb (SDT - 1548 - 54) 0.2mg 1 pc
SOB3398 Amyloid beta (N - terminal) Mouse mAb (SDT - R457) 0.2mg 1 pc

Host

Rabbit

Antigen

Amyloid beta 1-40

Synonyms

Aβ1-40

Immunogen

Synthetic Peptide

Accession

P05067

Clone Number

SDT-1548-52

Antibody Type

Recombinant mAb

Isotype

IgG

Application

Sandwich ELISA, CLIA

Reactivity ?

Hu, Ms

Cross Reactivity

No cross-reactivity against with Amyloid beta 1-42

Purification

Protein A

Concentration

2 mg/ml

Conjugation

Unconjugated

Physical Appearance

Liquid

Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Background
  • Amyloid beta 1-40 (Aβ1-40) is a 40-residue peptide derived from the amyloid precursor protein (APP) through sequential cleavage by β-secretase and γ-secretase. It is one of the major forms of amyloid beta peptides, along with Aβ1-42, and constitutes a significant portion of the amyloid plaques found in the brains of Alzheimer's disease patients. Unlike its more pathogenic counterpart Aβ1-42, Aβ1-40 is considered less prone to aggregation and plaque formation. However, it still plays a role in the disease pathology and has been implicated in neuroinflammation and cerebrovascular dysfunction. Additionally, Aβ1-40 has been found to have non-pathological functions and is more abundant in the brain compared to Aβ1-42.