Product Details
Product Details
Components
| Catalog Number | Commodity&Descriptions (Reagent/Antibodies) | Pack Size (ML/MG/UG) | Quantity (KIT/Bottle/PIECE) |
| SOB3392 | Amyloid beta 1 - 40 Recombinant Rabbit mAb (SDT - 1548 - 52) | 0.2mg | 1 pc |
| SOB3393 | Amyloid beta 1 - 40 Recombinant Rabbit mAb (SDT - 1548 - 54) | 0.2mg | 1 pc |
| SOB3398 | Amyloid beta (N - terminal) Mouse mAb (SDT - R457) | 0.2mg | 1 pc |
Host
Antigen
Synonyms
Immunogen
Accession
Clone Number
Antibody Type
Isotype
Application
Reactivity ?
Cross Reactivity
No cross-reactivity against with Amyloid beta 1-42
Purification
Concentration
Conjugation
Physical Appearance
Storage Buffer
PBS pH7.4, 0.03% Proclin 300
Stability & Storage
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
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Amyloid beta 1-40 (Aβ1-40) is a 40-residue peptide derived from the amyloid precursor protein (APP) through sequential cleavage by β-secretase and γ-secretase. It is one of the major forms of amyloid beta peptides, along with Aβ1-42, and constitutes a significant portion of the amyloid plaques found in the brains of Alzheimer's disease patients. Unlike its more pathogenic counterpart Aβ1-42, Aβ1-40 is considered less prone to aggregation and plaque formation. However, it still plays a role in the disease pathology and has been implicated in neuroinflammation and cerebrovascular dysfunction. Additionally, Aβ1-40 has been found to have non-pathological functions and is more abundant in the brain compared to Aβ1-42.
