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Samrotamab

Samrotamab

Catalog Number: UA011138 Brand: UA BIOSCIENCE
Price:
Regular price $80 USD
Regular price Sale price $80 USD
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Product Details

Product Specification


Synonyms ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamab vedotin
Expression System CHO
Molecular Weight

23-25kDa&47-53kDa (Reducing)

Purity >95% by SDS-PAGE
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, PH7.4, 5% trehalose
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.

Reference

1.Galvan M, Boer R, Schudt C. Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia. Eur J Pharmacol. 1989 Aug 11;167(1):1-10.

Background

Samrotamab (PR-1498487) is a humanized anti-LRRC15 antibody that can be used to synthesize the ADC compound (Samrotamab vedotin). It is a humanized IgG1-κ chimeric antibody targeting LRRC15.

Picture

SDS-PAGE

1μg (R: reducing condition, N: non-reducing condition).

ELISA

Immobilized LRRC15/LIB His Tag, Human (Cat. No. UA010915) at 10.0μg/mL (100μL/well) can bind Samrotamab (Cat. No. UA011138) with EC50 of 6.86-9.73ng/mL.

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