1μg (R: reducing condition).
NCAM-1/CD56 Fc Chimera Protein, Human
NCAM-1/CD56 Fc Chimera Protein, Human
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | CD56, MSK39, NCAM1, N-CAM-1 |
| Accession | P13591-2 |
| Amino Acid Sequence | Leu20-Gly718 with Human IgG1 Fc at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 110-130kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human IgG1 Fc |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1、Guven A. et al. (2021) Development and validation of an immunoassay for quantification of NCAM-1 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 197: 113981. |
Background
Neural Cell Adhesion Molecule 1 (NCAM-1), a multifunctional member of the immunoglobulin superfamily, is expressed on the surfaces of neurons, glial cells, skeletal muscle, and natural killer cells. NCAM-1 plays a role in cell-cell adhesion and is crucial for the development of the nervous system. It is also involved in the expansion of T cells and dendritic cells, which are key players in immune surveillance.
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SDS-PAGE
ELISA
Immobilized NCAM-1/CD56 Fc Chimera Protein, Human (Cat. No. UA010813) at 2.0μg/mL (100μL/well) can bind Biotinylated Lorvotuzumab with EC50 of 8.22-12.4 ng/mL.
Immobilized NCAM-1/CD56 Fc Chimera Protein, Human (Cat. No. UA010813) at 1.0μg/mL (100μL/well) can bind NCAM-1/CD56 Mouse mAb (S-577-58) (Cat. No. S0B0382) with EC50 of 2.37-3.64 ng/mL.
