• CD171 His Tag Protein, Human
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CD171 His Tag Protein, Human

CD171 His Tag Protein, Human

Catalog Number: UA010895 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE
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Product Details

Product Specification


Species Human
Synonyms CD171,L1CAM
Accession P32004
Amino Acid Sequence Ile20-Glu1120, with C-terminal His
Expression System HEK293
Molecular Weight 150-180kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Review Cell Adh Migr.2012 Jul-Aug;6(4):374-84. Epub 2012 Jul 1.

Background

L1 cell adhesion molecule (L1CAM), also known as CD171, is a cell adhesion receptor in the immunoglobulin superfamily, which plays an important role in the development of the nervous system. L1CAM interacts with a variety of ligands. Including axon protein 1, CD9, neurocan, and integrins. The molecule is a type I transmembrane (TM) protein that contains an 1101 aa extracellular region (aa 20-1120) plus a 114 aa cytoplasmic domain (aa 1144-1257). Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy.

Picture

SDS-PAGE

1μg (R: reducing condition, N: non-reducing condition).