Immobilized Human SIRPα Fc Chimera (Cat. No. UA010005) at 1 μg/mL (100 μL/well) can bind Biotinylated CD47 His Tag, Human with EC50 of 0.063 μg/ml.
Biotinylated CD47 His Tag Protein, Human
Biotinylated CD47 His Tag Protein, Human
Price:
Regular price
$702.00 SGD
Regular price
Sale price
$702.00 SGD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Antigenic surface determinant protein OA3, CD47 antigen, CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47, Integrin-associated protein, leukocyte surface antigen CD47 |
| Accession | Q08722 |
| Amino Acid Sequence | Gln19-Pro139, with C-terminal His&Avi Tag |
| Expression System | HEK293 |
| Molecular Weight | 30-35 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.2EU/μg |
| Conjugation | Biotin |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS pH7.2, 5% trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
CD47 (Cluster of Differentiation 47), also known as integrin associated protein (IAP), is a transmembrane protein that in humans is encoded by the CD47 gene. It belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. Also CD47 is ubiquitously expressed in human cells and has found to be overexpressed in many different tumor cells.
Picture
Picture
Bioactivity
SDS-PAGE
BIotinylated CD47 His Tag,Human,1μg on SDS-PAGE under reducing and Non-reducing contdition.The purity is greater than 95%.
