• Rabbit CD19, His tag
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Rabbit CD19, His tag

Rabbit CD19, His tag

Catalog Number: S0A1078 Brand: Starter
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$70 USD
$70 USD
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Product Details

Product Specification


Species Rabbit
Accession G1TWR4
Amino Acid Sequence

Protein sequence (G1TWR4, Gln21-Gly278, with C-10*His) QKLLQVEMEEGSDAVLPCLQDPPDGPPERLIWSRDSQGPFLELSPGSPGLGIHVGRLGILLLIFNVSNEMGGFYLCQPAPPSQQAWQPGWTVSVEGSGELFRWNASDLGGPGCGLGNESSSSQPYVWDRDHPKEWDMGPACASPRGDLNQSSSLDLTVAPGSTVWLSCGVPPASVATGPVSWAHIHPTKPNILLPSLNLTAESPAREMWVLGPVLMLPQVTAVDAGMYVCRRGNLTTEIHVTITVRPAIWHWLQRKSGGGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight Predicted MW: 29.5 kDa Observed MW: 40-65 kDa
Purity ＞95% by SDS-PAGE
Tag with C-10*His
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein. CD19 is expressed in all B lineage cells. CD19 plays two major roles in B cells: on the one hand, it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane; on the other, it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Picture

SDS-PAGE

2μg（R: reducing conditions）