1μg (R: reducing condition, N: non-reducing condition).
TPBG/5T4 His Tag Protein, Human
TPBG/5T4 His Tag Protein, Human
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$256 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | TPBG,5T4, M6P1,5T4AG, WAIF1 ,5T4 oncofetal trophoblast glycoprotein |
| Accession | Q13641 |
| Amino Acid Sequence | Ser32-Ser355 with His tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 50-72kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Li F, Wang Y, Cao J, Chen Q, Gao Y, Li R, Yuan L. Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis. Front Pharmacol. 2024 Jun 20; 15:1388205. |
Background
Trophoblast glycoprotein (TPBG), also known as 5T4, is a therapeutic target for several anticancer agents in clinical development. This is primarily due to its high expression in tumors and low expression in normal adult tissues. The TPBG gene encodes a leucine-rich transmembrane glycoprotein that may play a role in cell adhesion. TPBG is expressed by all types of trophoblasts as early as the ninth week of development.
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SDS-PAGE
SEC-HPLC
The purity of TPBG/5T4 His Tag Protein, Human is more than 95% determined by SEC-HPLC.
ELISA
Immobilized TPBG/5T4 His Tag Protein, Human (Cat. No. UA011109) at 2.0μg/mL (100μL/well) can bind TPBG Recombinant Monoclonal Antibody with EC50 of 1.26-2.59ng/mL.
