2μg (R: reducing condition, N:non-reducing condition).
MIS RII mFc Chimera Protein, Human
MIS RII mFc Chimera Protein, Human
Price:
Regular price
$281.00 SGD
Regular price
Sale price
$281.00 SGD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor |
| Accession | Q16671-1 |
| Amino Acid Sequence | Pro18-Ser144 with Mouse IgG2a Fc Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 48-60kDa (Reducing) |
| Purity | ＞90% by SDS-PAGE |
| Conjugation | Unconjugated |
| Tag | Mouse IgG2a Fc |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Zhao J, Feng B, Zheng MH, Xu K. Surgical robots for SPL and NOTES: a review. Minim Invasive Ther Allied Technol. 2015 Feb;24(1):8-17. |
Background
MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.
Picture
Picture
SDS-PAGE
