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Fibronectin His Tag Protein, Human

Fibronectin His Tag Protein, Human

Catalog Number: UA010252 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE
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Regular price $300 USD
Regular price Sale price $300 USD
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Product Details

Product Specification


Species Human
Synonyms Fibronectin, FN, CIG, FNZ, MSF
Accession P02751
Amino Acid Sequence Ser607-Pro1265, with C-terminal His
Expression System HEK293
Molecular Weight 78-85kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Zhou Y. et al. (2020) The effect and clinical significance of FN1 expression on biological functions of gastric cancer cells. Cell Mol Biol (Noisy-le-grand). 66(5): 191-198.

Background

FN1 (fibronectin 1) is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. It is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. In recent years, FN1 has been shown to play an important role in the regulation of various malignant tumors such as lung cancer, colorectal cancer, and ovarian cancer.

Picture

SDS-PAGE

2μg (R: reducing conditions, N: non-reducing conditions).

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