1μg (R: reducing condition).
Product Details
Product Details
Product Specification
Species | Human |
Synonyms | BTN1A1,Butyrophilin,BTN |
Accession | Q13410-1 |
Amino Acid Sequence | Ala27-Arg242 with His Tag at C-Terminus |
Expression System | HEK293 |
Molecular Weight | 30-37kDa(Reducing) |
Purity | > 95% as determined by SDS-PAGE & SEC-HPLC. |
Endotoxin | <0.1EU/μg |
Conjugation | Unconjugated |
Tag | His Tag |
Storage Buffer | PBS PH7.4 5% trehalose |
Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
Reference | Chu X, Han Z, Li B, Yang T. Plasma proteins and different onset subtype of COPD: Proteome-wide Mendelian randomization study and co-localization analyses. Medicine (Baltimore). 2025 May 9;104(19):e42409. |
Background
BTN1A1, also known as BTN, is a member of the immunoglobulin superfamily and the major milk fat droplet-associated protein. It may function as a cell surface receptor. The human butyrophilin gene, located in the MHC class I region on chromosome 6p, likely originated through exon shuffling between two ancestral gene families. BTN1A1 regulates milk lipid content and droplet size and inhibits proliferation of anti-CD3-activated CD4 and CD8 T-cells, as well as T-cell metabolism and secretion of IL2 and IFNG.
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SDS-PAGE
SEC-HPLC
The purity of BTN1A1/Butyrophilin His Tag Protein, Human is greater than 95% as determined by SEC-HPLC.
ELISA
Immobilized BTN1A1/Butyrophilin Monoclonal Antibody at 10.0μg/mL (100μL/well) can bind BTN1A1/Butyrophilin His Tag Protein, Human (Cat. No. UA011194) with EC50 of 2.90-4.47ng/mL.
