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BDNF Protein, Human/Mouse/Rat

BDNF Protein, Human/Mouse/Rat

Catalog Number: UA100029 Brand: UA BIOSCIENCE
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$294.00 SGD
$294.00 SGD
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Product Details

Product Specification


Species Human, Mouse, Rat
Synonyms Neurotrophic factor BDNF precursor form,proBDNF, Alternative names,Abrineurin,Brain-derived neurotrophic factor
Accession P23560
Amino Acid Sequence

His129-Arg247
Expression System E.coli
Molecular Weight

13 KDa
Purity >95% by SDS-PAGE
Endotoxin <0.01EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

20mM PB, 400mM NaCl, pH 7.2.
Reconstitution

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.

Reconstituted protein solution can be stored at 2-8°C for 2-7 days.

Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Stability & Storage


· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Background

Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.