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Human IL-15 PBS only Pairs Kit

Human IL-15 PBS only Pairs Kit

Catalog Number: S0J1008 Application: ELISA Reactivity: Human Conjugation: Unconjugated Brand: Starter
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Regular price $1,115 USD
Regular price Sale price $1,115 USD
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Product Details

Product Specification


Antigen IL-15

Kit


Range 15.63 pg/ml - 1000 pg/ml

Background

Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 is constitutively expressed by a large number of cell types and tissues, including monocytes, macrophages, dendritic cells (DC), keratinocytes, fibroblasts, myocyte and nerve cells. As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.

Picture

ELISA

Standard curve
Background subtracted standard curve using IL-15 PBS only Pairs in sandwich ELISA.
The ELISA was performed using the components of the corresponding
OneStep kit (S0C3014), which uses the same antibody pair with a different formulation and format.

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