2μg（R: reducing conditions）
Mouse M-cadherin/cadherin-15 Protein, His tag
Mouse M-cadherin/cadherin-15 Protein, His tag
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$185.00 USD
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Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | Cadherin-15, Cadherin-14, Muscle cadherin (M-cadherin), Cdh15, Cdh14 |
| Accession | P33146 |
| Amino Acid Sequence | Protein sequence (P33146, Val22-Ala605, with C-His tag) VPEPKPSTLYPWRRASAPGRVRRAWVIPPISVSENHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRNVFSIDKFTGRVYLNATLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQDVFRGRILEGAIPGTFVTRAEATDADDPETDNAALRFSILEQGSPEFFSIDEHTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIISIDDINDNAPEFTKDEFFMEAAEAVSGVDVGRLEVEDKDLPGSPNWVARFTILEGDPDGQFKIYTDPKTNEGVLSVVKPLDYESREQYELRVSVQNEAPLQAAAPRARRGQTRVSVWVQDTNEAPVFPENPLRTSIAEGAPPGTSVATFSARDPDTEQLQRISYSKDYDPEDWLQVDGATGRIQTQRVLSPASPFLKDGWYRAIILALDNAIPPSTATGTLSIEILEVNDHAPALALPPSGSLCSEPDQGPGLLLGATDEDLPPHGAPFHFQLNPRVPDLGRNWSVSQINVSHARLRLRHQVSEGLHRLSLLLQDSGEPPQQREQTLNVTVCRCGSDGTCLPGAAALRGGGVGVSLGA |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 65.4 kDa Observed MW: 95 kDa |
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-His tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Cadherin-15 is a protein that is encoded by the CDH15 gene. This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
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