3μg（R: reducing conditions）
Mouse CD3 epsilon Protein, hFc tag
Mouse CD3 epsilon Protein, hFc tag
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$225.00 USD
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Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e |
| Accession | P22646 |
| Amino Acid Sequence | Protein sequence (P22646, Asp23-Asp108, with C-hFc tag) DAENIEYKVSISGTSVELTCPLDSDENLKWEKNGQELPQKHDKHLVLQDFSEVEDSGYYVCYTPASNKNTYLYLKARVCEYCVEVD |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 36 kDa Observed MW: 43 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-hFc tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
CD3e molecule, epsilon also known as CD3E. The protein is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause severe immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. T-cell surface glycoprotein CD3 epsilon chain has been shown to interact with TOP2B, CD3EAP and NCK2.
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SDS-PAGE
