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Mouse BST2 Protein, His tag

Mouse BST2 Protein, His tag

Catalog Number: S0A1133 Reactivity: Mouse Conjugation: Unconjugated Brand: Starter
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Regular price $225.00 USD
Regular price Sale price $225.00 USD
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Product Details

Product Specification


Species Mouse
Synonyms Bone marrow stromal antigen 2, BST-2, HM1.24 antigen, CD317
Accession Q8R2Q8
Amino Acid Sequence

Protein sequence (Q8R2Q8, Ala53-Asn151, with C-His tag) ANSVACRDGLRAQAECRNTTHLLQRQLTRTQDSLLQAETQANSCNLTVVTLQESLEKKVSQALEQQARIKELENEVTKLNQELENLRIQKETSSTVQVN

Expression System HEK293
Molecular Weight Predicted MW: 12.9 kDa Observed MW: 18-25 kDa
Purity >90% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag with C-His tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Bone marrow stromal antigen 2, also known as CD317, is a lipid raft associated protein that is encoded by the BST2 gene. This protein is constitutively expressed in mature B cells, plasma cells and plasmacytoid dendritic cells, and in many other cells, it is only expressed as a response to stimuli from IFN pathway. BST2 is a cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 has been shown as a Type-I-IFN biomarker using flow cytometry, B cell BST2 was used as a Cell-Specific Assay for Response to Type I Interferon Predicts Clinical Features and Flares in Systemic Lupus Erythematosus. BST2 has also been predicted to be involved in cell adhesion and cell migration. It has also been identified as the protein that help stabilize lipid rafts by joining nearby lipid rafts to form a cluster.

Picture

SDS-PAGE

2μg(R: reducing conditions)

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