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Monkeypox virus(MPXV E8L) Recombinant Human mAb

Monkeypox virus(MPXV E8L) Recombinant Human mAb

Catalog Number: S0B0001 Application: ELISA Brand: Starter
Price:
Regular price $100.00 USD
Regular price Sale price $100.00 USD
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Product Details

Product Specification


Host Human
Antigen Monkeypox Virus EBL
Immunogen N/A
Accession Q8V4Y0
Clone Number SDT-R008
Antibody Type Human mAb
Application ELISA
Reactivity MPXV
Purification Protein A
Research Area Monkeypox Virus
Concentration 2.0mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
ELISA ELISA: 0.01-0.5μg/ml null

Background

Monkeypox is a rare disease similar to smallpox caused by the monkeypox virus. It’s found mostly in areas of Africa, but has been seen in other regions of the world. It causes flu-like symptoms such as fever and chills, and a rash that can take weeks to clear. There’s no proven treatment for monkeypox, but it usually goes away on its own.Monkeypox Virus E8L binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell. Antibody targeting D8, H3 and A27 (VACV) are able to block the viral adhesion to the host cell and thereforprotect from infection. Anti-MPXV E8L mAb is a human monoclonal antibody and is produced by mammalian expression system.

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Validation Data

Anti-Monkeypox virus(MPXV E8L) Antibody (dilutions start from 2ug/ml) can bind to immobilized Monkeypox virus E8L, His tag (S0A2018) at 1μg/ml (50μL/well) as coating antigen.

EC50=31.59 ng/ml

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