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LAMP1 Recombinant Rabbit mAb (PE Conjugate) (SDT-405-39)

LAMP1 Recombinant Rabbit mAb (PE Conjugate) (SDT-405-39)

Catalog Number: S0B1772 Application: FCM Reactivity: Human Conjugation: PE Brand: Starter
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Regular price $185.00 USD
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Product Details

Product Specification


Host Rabbit
Antigen LAMP1
Synonyms Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; CD107a
Immunogen Recombinant Protein
Location Cell membrane
Accession P11279
Clone Number SDT-405-39
Antibody Type Recombinant mAb
Isotype IgG
Application ICFCM
Reactivity Hu
Positive Sample HeLa
Purification Protein A
Concentration 1 mg/ml
Conjugation PE
Physical Appearance Liquid
Storage Buffer PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
ICFCM 1:400 Hu

Background

Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The LAMP-1 glycoprotein is a type I transmembrane protein [PMID: 16973206] which is expressed at high or medium levels in at least 76 different normal tissue cell types. It resides primarily across lysosomal membranes [PMID: 2584229], and functions to provide selectins with carbohydrate ligands. LAMP-1 has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells, and may also play a role in tumor cell differentiation and metastasis.

Picture

FC

Flow cytometric analysis of LAMP1 expression on 4% PFA fixed 90% methanol permeabilized HeLa cells. Cells from the HeLa (Human cervix adenocarcinoma epithelial cell) was stained with Phycoerythrin Rabbit IgG Isotype Control (Black line histogram) and SDT LAMP1 Recombinant Rabbit mAb (PE Conjugate) (Red line histogram) at 1/400 dilution (0.25 μg), cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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