WB result of IL-13RA2/CD213a2 Rabbit pAb
Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
Lane 1: Daudi whole cell lysate 20 µg
Lane 2: A375 whole cell lysate 20 µg
Lane 3: U-87 MG whole cell lysate 20 µg
Lane 4: HeLa whole cell lysate 20 µg
Negative control: Daudi whole cell lysate
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
Observed MW: 70 kDa
IL-13RA2/CD213a2 Rabbit Polyclonal Antibody
IL-13RA2/CD213a2 Rabbit Polyclonal Antibody
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | IL-13RA2/CD213a2 |
| Synonyms | Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; Interleukin-13-binding protein |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q14627 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | A375, U-87, HeLa, mouse testis, rat testis |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
Background
IL-13RA2, or Interleukin 13 Receptor Alpha 2, is a protein that has gained significant attention for its role in cancer and as a potential therapeutic target. IL-13RA2 is overexpressed in various cancers, including melanoma, renal cell carcinoma, adrenocortical carcinoma, and several brain tumors. Its expression is associated with tumor invasion, metastasis, and poor prognosis. Unlike the IL-13Rα1, which activates the JAK/STAT pathway, IL-13RA2 was considered a non-signaling receptor due to its short intracellular domain. However, it has been shown to participate in signaling pathways that promote tumor progression, such as those involving AP-1 and ERK.
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Western Blot
WB result of IL-13RA2/CD213a2 Rabbit pAb
Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
Lane 1: mouse testis lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
Observed MW: 70 kDa
WB result of IL-13RA2/CD213a2 Rabbit pAb
Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
Lane 1: rat testis lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
Observed MW: 70 kDa
