Measured in a cell proliferation assay using TF-1 human erythroleukemic cells, the EC50 for this effect is less than 2ng/ml.
IL-13 Protein, Mouse
IL-13 Protein, Mouse
Price:
Regular price
$192.00 USD
Regular price
Sale price
$192.00 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | Interleukin-13, ALRH Protein, Human; IL-13 Protein, Human; P600 Protein, Human |
| Accession | P20109 |
| Amino Acid Sequence | Ser26-Phe131 |
| Expression System | E.coli |
| Molecular Weight | 12kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 300mM NaCl, pH6.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Cells. 2021 Nov 3;10(11):3000. |
Background
IL-13 is the signature cytokine of the type II inflammatory response. It is key player in the inflammatory response triggered either by an invading parasite or allergen. The cellular sources of IL-4 and IL-13 have been studied extensively and along with CD4 T cells, basophils, eosinophils, mast cells, and NK T cells, appropriately stimulated ILC2 cells have the ability to produce IL-4 and IL-13. IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important immunomodulatory activities and exert influence on a wide variety of immune cells, such as B cells, eosinophils, basophils, monocytes, fibroblasts, endothelial cells, airway epithelial cells, smooth muscle cells, and keratinocytes.
Picture
Picture
Bioactivity
SDS-PAGE
2μg (R: reducing condition, N: non-reducing condition).
SPR
Anti-His antibody Immobilized on CM5 Chip captured IL-13RA1 His Tag Protein, Mouse (Cat. No. UA011052), can bind IL-13 Protein, Mouse (Cat. No. UA040158) with an affinity constant of 2.08nM as determined in SPR assay.
