2μg（R: reducing conditions）
α-Synuclein Protein, Mouse
α-Synuclein Protein, Mouse
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$76.00 USD
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Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor (NACP), Snca, Syn,alpha-Synuclein |
| Accession | O55042 |
| Amino Acid Sequence | Met1-Ala140 |
| Expression System | E.coli |
| Molecular Weight | Predicted MW: 14.5 kDa Observed MW: 17 kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 0.2M PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. It plays a role in restricting the mobility of synaptic vesicles, consequently attenuating synaptic vesicle recycling and neurotransmitter release.
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SDS-PAGE
ELISA
Immobilized α-Synuclein Protein, Mouse at 1 μg/mL (100 μL/well) can bind α-Synuclein Recombinant Rabbit mAb (S-441-86) (Cat. No. S0B0344) with EC50 of 1.0-1.3 ng/ml.
