Premium Anti-Symmetric Dimethyl Arginine agarose Beads
Premium Anti-Symmetric Dimethyl Arginine agarose Beads
Product Details
Product Details
Product Specification
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Reactivity | Species Independent |
| Purification | Protein A |
| Physical Appearance | Liquid |
| Storage Buffer | 50% slurry in PBS pH7.4, 0.05% Proclin 300. Ensure thorough mixing before each use. Wide-mouth pipette tips are recommended. In case of difficulty in aspiration due to improper operation, additional Storage Buffer can be added at your discretion. |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Symmetric Dimethylarginine (SDMA) is a methylated derivative of the amino acid arginine, formed through post-translational modification of proteins. Historically considered inactive, it is now primarily recognized as a highly sensitive and specific endogenous biomarker for renal function, particularly glomerular filtration rate (GFR). SDMA is freely filtered by the glomeruli and is not secreted by the renal tubules, making it a more accurate indicator of renal filtration than serum creatinine, as it is less influenced by non-renal factors such as muscle mass, diet, or sex. Its measurement is increasingly valuable in the early detection and monitoring of both acute kidney injury and chronic kidney disease in human and veterinary medicine.
