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FCAR/CD89 His Tag Protein, Human

FCAR/CD89 His Tag Protein, Human

Catalog Number: UA020007 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE
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Regular price $560 USD
Regular price Sale price $560 USD
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Product Details

Product Specification


Species Human
Synonyms Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR
Accession P24071-1
Amino Acid Sequence Gln22-Asn227, with C-terminal His
Expression System HEK293
Molecular Weight 42-55 kDa(Reducing)
Purity >95%, by SDS-PAGE under reducing conditions
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

FCAR, also known as Fc alpha RI or CD89, is a 50-100 kDa glycosylated bone marrow-specific type I transmembrane (TM) Fc receptor, which is a member of the immunoglobulin gene superfamily. FCAR exists on the surface of myeloid cells such as neutrophils, monocytes, macrophages and eosinophils, and mediates the immune response to pathogens. It interacts with IgA-regulated targets and triggers a variety of immune defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity and stimulating the release of inflammatory mediators. This product is made by recombinant expression of human FCAR from HEK293 cell line, purified, sterilized, filtered, packaged and freeze-dried.

Picture

SDS-PAGE

FCAR/CD89 His Tag, Human,1μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.

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