CD4+T cells were enriched or depleted from human PBMCs. CD4+ cells were stained withanti-CD4 (clone: RPAT4) Brilliant Violet 421™ and gated on Live+.
Product Details
Product Details
Product Specification
| Stability & Storage | Store protected from light at 2 to 8 °C. Do not freeze. |
Background
CD4 NanoBeads have been developed for the separation of human cells based on the expression of the CD4 antigen. CD4 is a 55 kDa protein that is highly expressed on T helper cells in the thymus and peripheral blood. In T helper cells, CD4 functions as an accessory molecule for the recognition of MHC class II/peptide complexes by TCR heterodimers. CD4 is also expressed on monocytes and dendritic cells, albeit at lower levels than on CD4+ T helper cells. In conjunction with certain chemokine receptors, CD4 is the primary high-affinity receptor for HIV.
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Validation Data
