1μg (R: reducing condition, N: non-reducing condition).
Biotinylated CDH17/LI-cadherin His&Avi Tag Protein, Human
Biotinylated CDH17/LI-cadherin His&Avi Tag Protein, Human
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Cadherin-17, HPT-1 |
| Accession | Q12864 |
| Amino Acid Sequence | Gln23-Met787, with C-10*His and Avi tag |
| Expression System | HEK293 |
| Molecular Weight | 95-100kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Chen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2. 2. Long Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705. |
Background
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. It's also involved in intestinal peptide transport.
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SDS-PAGE
ELISA
Immobilized Biotinylated CDH17/LI-cadherin His&Avi Tag, Human (Cat. No. UA010744) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Cadherin 17 Recombinant Rabbit mAb (SDT-736-23) (Cat. No. S0B2291) with EC50 of 19.73-27.06ng/ml.
