TSLP Recombinant Rabbit mAb (SDT-2587-67)
TSLP Recombinant Rabbit mAb (SDT-2587-67)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | TSLP |
| Synonyms | Thymic stromal lymphopoietin; TSLP |
| Immunogen | Recombinant Protein |
| Accession | Q969D9 |
| Clone Number | SDT-2587-67 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against IL-6, IFN-γ, GM-CSF |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
TSLP (thymic stromal lymphopoietin) is a four-helix-bundle cytokine of the IL-2 family that is chiefly produced by epithelial cells at barrier surfaces; it acts on dendritic cells, mast cells, and type 2 innate lymphoid cells via a receptor complex of TSLPR plus IL-7Rα to trigger STAT5-driven transcriptional programs, thereby polarizing naïve CD4⁺ T cells toward a pro-allergic Th2 phenotype, orchestrating eosinophilic inflammation, and serving as a master switch for atopic dermatitis, asthma, and other allergic diseases.
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