PE Mouse Anti-Human CD13 Antibody (S-689-37)

CD13, also known as aminopeptidase N, is a 150 kDa type II transmembrane metalloprotease expressed on myeloid cells, endothelial cells, fibroblasts, and epithelial cells, functioning both as a Zn²⁺-dependent ectoenzyme that trims N-terminal amino acids from peptides such as cytokines, chemokines, and hormones to modulate their bioactivity, and as a signaling adhesion molecule that regulates immune cell trafficking, inflammatory responses, cell–cell fusion (e.g., syncytiotrophoblast, myotube, and osteoclast formation), and receptor recycling, thereby exerting context-dependent roles in tissue repair, angiogenesis, and pathologic inflammation.