Flow cytometric analysis of human peripheral blood Leukocytes labelling Human XCR1 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2a, κ Isotype Control / (left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD141 - APC antibody separately.
Rat Anti-Human XCR1 Antibody (S-3294)
Rat Anti-Human XCR1 Antibody (S-3294)
Price:
Regular price
$131.00 SGD
Regular price
Sale price
$131.00 SGD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | XCR1 |
| Synonyms | Chemokine XC receptor 1; G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1; CCXCR1; GPR5 |
| Location | Cell membrane |
| Accession | P46094 |
| Clone Number | S-3294 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human peripheral blood Leukocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
XCR1 is a conserved, 7-transmembrane G-protein-coupled receptor selectively expressed on CD8α⁺ and CD103⁺ classical dendritic cells; its exclusive ligand XCL1 is secreted by activated CD8⁺ T and NK cells, forming a chemotactic feedback loop that recruits antigen-loaded DCs into lymphoid tissue and optimizes cross-presentation, Th1 cytotoxicity and antiviral/antitumor immunity, making the XCR1–XCL1 axis an emerging target for cancer immunotherapy and vaccine adjuvant design.
Picture
Picture
FC
