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Pacific Blue Mouse Anti-Human CD41a Antibody (S-R554)

Pacific Blue Mouse Anti-Human CD41a Antibody (S-R554)

Catalog Number: S0B8157 Application: FCM Reactivity: Human Conjugation: Pacific Blue Brand: Starter
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$275.00 SGD
$275.00 SGD
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Product Details

Product Specification


Host Mouse
Antigen CD41a
Synonyms Integrin alpha-IIb; GPalpha IIb (GPIIb); Platelet membrane glycoprotein IIb; CD41; GP2B; ITGAB; ITGA2B
Location Membrane
Accession P08514
Clone Number S-R554
Antibody Type Mouse mAb
Isotype IgG1
Application FCM
Reactivity Hu
Positive Sample Human peripheral blood platelets
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD41a, also known as platelet glycoprotein IIb, is a crucial component of the GPIIb/IIIa complex on the platelet membrane. It is a calcium-dependent protein that pairs with CD61 to form the functional fibrinogen receptor, playing a vital role in platelet aggregation and blood clotting. This complex is primarily expressed in normal platelets and megakaryocytes. Additionally, CD41a is one of the first cell surface markers indicative of hematopoietic commitment and is involved in maintaining hematopoietic stem cell activity during embryonic development.

Picture

FC

Flow cytometric analysis of Human CD41a expression on human peripheral blood platelets. Human peripheral blood platelets were stained with either Pacific Blue Mouse IgG1, κ Isotype Control (Black line histogram) or SDT Pacific Blue Mouse Anti-Human CD41a Antibody (Red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.