Mouse IL-13 Recombinant mAb (SDT-2177-24)
Mouse IL-13 Recombinant mAb (SDT-2177-24)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Mouse IL-13 |
| Synonyms | Interleukin-13; T-cell activation protein P600 |
| Immunogen | Recombinant Protein |
| Clone Number | SDT-2177-24 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Ms |
| Cross Reactivity | No cross-reactivity against mouse GM-CSF, IL-1β, IL-1α |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
IL-13 (Interleukin-13) is a key cytokine primarily produced by activated Th2 cells, mast cells, and basophils. It is a central mediator in type 2 immune responses, playing a critical role in the pathogenesis of allergic inflammation. Its main functions include inducing IgE class switching in B cells, promoting mucus hypersecretion in airway epithelial cells, and contributing to tissue fibrosis by stimulating fibroblast proliferation and collagen production. Furthermore, IL-13 is instrumental in the defense against helminthic parasites by facilitating their expulsion from the gastrointestinal tract.
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