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FITC Mouse Anti-Human CD181 Antibody (S-3490)

FITC Mouse Anti-Human CD181 Antibody (S-3490)

Catalog Number: S0B8068 Application: FCM Reactivity: Human Conjugation: FITC Brand: Starter
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$183.00 SGD
$183.00 SGD
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Product Details

Product Specification


Host Mouse
Antigen CD181
Synonyms C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; CDw128a; High affinity interleukin-8 receptor A (IL-8R A); IL-8 receptor type 1; CMKAR1; IL8RA; CXCR1
Location Cell membrane
Accession P25024
Clone Number S-3490
Antibody Type Mouse mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Positive Sample Human peripheral blood Leukocytes
Purification Protein A
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD181, also known as CXCR1, is a 67–70 kDa G-protein-coupled receptor that selectively binds the chemokine interleukin-8 (IL-8) and mediates rapid neutrophil activation, chemotaxis and respiratory burst through Gαi-triggered calcium flux and phospholipase D signaling; expressed on granulocytes, NK cells, monocytes, endothelial cells and oligodendrocytes, it functions as a homodimer or heterodimer with CD182 (CXCR2), and its sustained up-regulation has been implicated in systemic lupus erythematosus-associated hemolytic anemia and other inflammatory disorders.

Picture

FC

Flow cytometric analysis of Human CD181 expression on human peripheral blood Leukocytes. Human peripheral blood Leukocytes were stained with either FITC Mouse IgG2b, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD181 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.