Mouse Immune Cell Depletion Antibodies For in vivo Use

07 Jun 2025 by AntBio

Starter provides a range of monoclonal antibodies targeting mouse cell surface proteins, designed for in vivo depletion of specific cell types. These in vivo cell - specific depletion experiments are widely used to determine the role of specific cell types in various immunological processes and diseases.

These antibodies are developed for in vivo research and can deplete specific cell types through injection. Such experiments not only extend and verify the results obtained from gene - knockout mouse models but also offer significant evidence for the direct biological relevance of specific cell types.

These antibodies mediate cell depletion through various mechanisms, including antibody - dependent cell - mediated cytotoxicity (ADCC), complement - dependent cytotoxicity (CDC), and antibody - dependent cell phagocytosis (ADCP).

Cell Type	Target	Clone	Catalog Numbers
B Cells	B220	RA3.3A1/6.1	BE0067
	CD19	1D3	BE0150
	CD20	MB20-11	BP0356
T Cells	CD3e	145-2C11	S0B0661
	Thy1.2 (CD90.2)	30H12	BP0066
	Thy1.1 (CD90.1)	1.90E+13	BE0214
	Thy1 (CD90)	M5/49.4.1	BE0076
	TCR β	H57-597	BE0102
CD4+T Cells	CD4	GK1.5	S0B0690
CD4+T Cells	CD4	YTS 191	BE0119
CD8+T Cells	CD8a	2.43	S0B0660
	CD8a	S-R540	S0B1141
	CD8a	YTS 169.4	BP0117
	CD8 (Lyt 2.1)	116-13.1	BE0118
	CD8β	S-R484	S0B1032
TReg Cells	CD25 (IL-2Rβ)	S-R441	S0B0873
γδ T Cells	Vγ2 TCR	UC3-10A6	BE0168
ILCs	Thy1.2 (CD90.2)	30H12	BP0066
NK Cells	NK1.1	S-R480	S0B0998
NK Cells	CD122 (IL-2Rβ)	TM-beta 1	BE0298
Neutrophils	Ly6G	S-R481	S0B0981
	Ly6G/Ly6C (Gr-1)	S-R425	S0B0838
	Ly6G/Ly6C	NIMP-R14	BE0320
Eosinophils	IL-5	TRFK5	BE0198
Eosinophils	CCR3 (CD193)	6S2-19-4	BE0316
Macrophages	CSF1R	S-R562	S0B1139
	F4/80	CI:A3-1	BE0206
	Ly6C	Monts 1	BE0203
Monocytes	Ly6G/Ly6C (Gr-1)	S-R425	S0B0838
	CSF1R	S-R562	S0B1139
	F4/80	CI:A3-1	BE0206
Plasmacytoid Dendritic Cells	CD317 (PDCA-1)	927	BE0311
Mast Cell	c-Kit	ACK2	BE0293