1μg (R: reducing condition, N: non-reducing condition).
TREM-1/CD354 Fc Chimera Protein, Mouse
TREM-1/CD354 Fc Chimera Protein, Mouse
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Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | CD354 antigen; CD354; TREM1; TREM-1; TREM-1Triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1 |
| Accession | Q9JKE2 |
| Amino Acid Sequence | Ala21-Ser202 with Human IgG1 Fc at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 55-72kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE &＞95% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Huamn IgG1 Fc |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol. 2000;164:4991–5. |
Background
The TREM-1 protein, a pivotal cell surface receptor, plays a crucial role in amplifying inflammatory responses within both the innate and adaptive immune systems. Activation of TREM-1 by ligands such as PGLYRP1, HMGB1, or HSP70 triggers multimerization of the receptor and subsequent complex formation with the signaling adaptors TYROBP (also known as DAP12).
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SDS-PAGE
SEC-HPLC
The purity of TREM-1/CD354 Fc Chimera Protein, Mouse is greater than 95% as determined by SEC-HPLC.
