1μg (R: reducing condition, N: non-reducing condition).
TIMP-2 Protein, Human
TIMP-2 Protein, Human
Price:
Regular price
$236 USD
Regular price
Sale price
$236 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | CSC-21K,TIMP2 |
| Accession | P16035 |
| Amino Acid Sequence | Cys27-Pro220, with C-terminal His Tag |
| Expression System | HEK293 |
| Molecular Weight | 22-24 kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE and HPLC. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, 5% trehalose, PH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Sci Rep . 2021 Jan 13;11(1):1071. |
Background
TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. The total length of TIMP-2 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of 22-24 kDa. TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors.
Picture
Picture
SDS-PAGE
RP-HPLC
99.451%
