Tau (phospho T205) Recombinant Rabbit mAb (SDT-2034-24)
Tau (phospho T205) Recombinant Rabbit mAb (SDT-2034-24)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Tau (phospho T205) |
| Synonyms | p-Tau205, pTau205 |
| Immunogen | Synthetic Peptide |
| Clone Number | SDT-2034-24 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Predicted Reactivity | Ms |
| Cross Reactivity | No cross-reactivity against total Tau, p-Tau181, p-Tau217, p-Tau231. |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Serum and CSF p-tau205 is a highly specific biomarker of AD, exhibiting a continuous and steep increase along with AD progression. Most importantly, it accurately reflects in vivo tau burden, thereby suggesting its potential usefulness identifying and staging tau pathology in AD. Thus, a high throughput method such as the digital immunoassays using pTau205 antibody and total tau antibody as sandwich pairs would be of great use in clinical settings and clinical trials.
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