The SOS2 activity was detected using HTRF technology. The reaction was performed by incubating the varying concentration of MRTX1133, SOS2 protein, KRAS[G12C] and beads at 25℃ for 60 min, then reading ratio 665/620 with BMG.
SOS2, GST Tag Protein
SOS2, GST Tag Protein
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | FLJ25596; guanine nucleotide exchange factor; guanine nucleotide releasing factor; son of sevenless (Drosophilia) homolog 2; son of sevenless homolog 2 (Drosophila); son of sevenless homolog 2; SOS2; SOS-2 |
| Accession | Q07890 |
| Amino Acid Sequence | T654-G1043 |
| Expression System | E.coli |
| Molecular Weight | 82511.0 |
| Purity | >90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | GST Tag |
| Physical Appearance | Liquid |
| Storage Buffer | 50 mM Tris, PH7.4, 300 mM NaCl, 2 mM DTT, 10% glycerol |
| Stability & Storage | -80℃ |
Picture
Picture
Bioactivity
SDS-PAGE
M MW Standard
1 1 μg SOS2
2 3 μg SOS2
