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SLAMF8 Recombinant Rabbit mAb (S-1956-78)

SLAMF8 Recombinant Rabbit mAb (S-1956-78)

Catalog Number: S0B1406 Application: WB Reactivity: Mouse,Rat Conjugation: Unconjugated Brand: Starter
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Regular price $130.00 SGD
Regular price Sale price $130.00 SGD
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Product Details

Product Specification


Host Rabbit
Antigen SLAMF8
Synonyms SLAM family member 8; B-lymphocyte activator macrophage expressed; BCM-like membrane protein; CD353; BLAME
Immunogen Synthetic Peptide
Location Membrane
Accession Q9P0V8
Clone Number S-1956-78
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Ms, Rt
Positive Sample mouse lung, mouse thymus, mouse spleen, rat lung, rat thymus, rat spleen
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Ms, Rt

Background

SLAMF8, also known as B-lymphocyte activator macrophage expressed (BLAME) or CD353, is a single-pass type I membrane protein belonging to the SLAM (Signaling Lymphocyte Activation Molecule) family. It is characterized by the presence of Ig-like domains and is primarily expressed in immune-related tissues such as the lymph node, spleen, and thymus. SLAMF8 has been identified as a potential new immune checkpoint molecule, with its high expression associated with poor prognosis in colorectal cancer. This protein is involved in immune regulation and may play a role in various immune responses, including those related to inflammation and autoimmune diseases.

Picture

Western Blot

WB result of SLAMF8 Recombinant Rabbit mAb
Primary antibody: SLAMF8 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: mouse lung lysate 20 µg
Lane 2: mouse thymus lysate 20 µg
Lane 3: mouse spleen lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 32 kDa
Observed MW: 25 kDa

WB result of SLAMF8 Recombinant Rabbit mAb
Primary antibody: SLAMF8 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: rat lung lysate 20 µg
Lane 2: rat thymus lysate 20 µg
Lane 3: rat spleen lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 32 kDa
Observed MW: 25 kDa

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