SCF Protein, Human

Catalog Number: UA040138 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE

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$136 USD

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Product Details

Product Specification

Species	Human
Synonyms	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7, KL
Accession	P21583
Amino Acid Sequence	Glu26-Ala189
Expression System	E.coli
Molecular Weight	19kDa
Purity	>95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 200mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1. Review Physiol Rev. 2012 Oct;92(4):1619-49.

Background

Stem Cell Factor is also known as SCF, kit-ligand, KL, steel factor, KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, or SHEP7, and is a cytokine that binds to the c-Kit receptor (CD117). Stem cell factors perform their biological functions by binding to and activating the receptor tyrosine kinase c-Kit. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. Stem cell factor (SCF) has been shown to stimulate the proliferation of myeloid, erythroid, and lymphoid progenitor cells in bone marrow culture and has been shown to work synergically with colony-stimulating factors.