Product Specification
| Host |
Rabbit |
| Antigen |
SARS-CoV-2 |
| Immunogen |
Recombinant Protein |
| Accession |
P0DTC9 |
| Clone Number |
SDT-021-91 |
| Antibody Type |
Rabbit mAb |
| Application |
Lateral Flow |
| Reactivity |
SARS-CoV-2 |
| Cross Reactivity |
Do not cross react with Mers-CoV N Protein, HcoV-HKU N Protein, HcoV-NL63 N Protein, HcoV-OC43 N Protein and HCoV-229E N Protein. |
| Purification |
Protein A |
| Concentration |
2mg/ml |
| Purity |
>95% by HPLC |
| Conjugation |
Unconjugated |
| Storage Buffer |
PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage |
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application |
dilution |
species |
| Lateral Flow |
N/A |
|
Background
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The nucleocapsid (N) protein is a protein that packages the positive-sense RNA genome of coronaviruses to form ribonucleoprotein structures enclosed within the viral capsid. The N protein is the most highly expressed of the four major coronavirus structural proteins. In addition to its interactions with RNA, N forms protein-protein interactions with the coronavirus membrane protein (M) during the process of viral assembly. N also has additional functions in manipulating the cell cycle of the host cell. The N protein is highly immunogenic and antibodies to N are found in patients recovered from SARS and Covid-19.