Renin Recombinant Rabbit mAb (SDT-087-12)
Renin Recombinant Rabbit mAb (SDT-087-12)
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$335 USD
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Renin |
| Synonyms | Angiotensinogenase |
| Immunogen | Recombinant Protein |
| Accession | P00797 |
| Clone Number | SDT-087-12 |
| Antibody Type | Rabbit mAb |
| Application | ELISA |
| Reactivity | Hu |
| Cross Reactivity | Do not cross react with Serpin A8 |
| Purification | Protein A |
| Concentration | 2mg/ml |
| Purity | >95% by HPLC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS , 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ELISA | N/A |
Background
Renin, also known as angiotensinogen enzyme, is a proteolytic enzyme released by paraspheroidal granulosa cells and is part of the renin-angiotensin system. Renin acts on plasma angiotensingen to produce inactive angiotensin I, which is hydrolyzed to active angiotensin II under the action of angiotensin converting enzyme. Angiotensin II can cause arteriolar vasoconstriction and promote the synthesis and secretion of aldosterone in adrenal cortex. Plasma Renin activity test can be used to diagnose primary aldosteronism and hypertension.
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