Product Details
Product Details
Product Specification
| Host | Mouse |
| Antigen | Rat IgM |
| Clone Number | S-3601 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | ELISA |
| Reactivity | Rt |
| Purification | Protein G |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 1:5000-1:10000 | Rt |
Background
Rat IgM is a high-molecular-weight, pentameric immunoglobulin composed of five μ-heavy-chain-based monomers linked by disulfide bonds and a joining (J) chain; it is the first antibody isotype secreted during the primary immune response, where it provides low-affinity but broad-reactivity pathogen recognition, potently activates the classical complement pathway, and serves as the B-cell antigen receptor on naïve rat B lymphocytes.
