Rat IFN-γ Recombinant mAb (SDT-1970-57)
Rat IFN-γ Recombinant mAb (SDT-1970-57)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Rat IFN-γ |
| Synonyms | Interferon gamma; IFN-gamma |
| Immunogen | Recombinant Protein |
| Accession | P01581 |
| Clone Number | SDT-1970-57 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Rt |
| Cross Reactivity | No cross-reactivity against rat IL-6, rat TNF-alpha, rat IL-1beta, rat IL-2 and mouse IFN-γ |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Rat IFN-γ (Interferon gamma) is a multifunctional cytokine primarily produced by activated T-lymphocytes and natural killer cells. It plays a crucial role in the immune response, exhibiting antiviral, antitumor, and immunoregulatory activities. Rat IFN-γ exists as a homodimer with a molecular weight of approximately 15.6 kDa and is highly species-specific. It upregulates the expression of MHC class I and II molecules, enhances macrophage activation, and promotes the secretion of immunoglobulins by B cells. The protein is also involved in cytokine regulation and acts synergistically with other cytokines. Rat IFN-γ is used in research for studying immune responses and related diseases.
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