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Rat Anti-Mouse CD309 Antibody (S-R706)

Rat Anti-Mouse CD309 Antibody (S-R706)

Catalog Number: S0B8356 Application: FCM Reactivity: Ms Conjugation: Unconjugated Brand: Starter
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Regular price $37 USD
Regular price Sale price $37 USD
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Product Details

Product Specification


Host Rat
Antigen CD309
Synonyms Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1 (FLK-1); Kinase NYK; Protein-tyrosine kinase receptor flk-1; Flk-1; Flk1; Kdr
Location Cell junction
Accession P35918
Clone Number S-R706
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample bEnd.3
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Ms

Background

CD309, also known as VEGFR-2 or KDR, is a type III receptor tyrosine kinase that functions as the primary mediator of VEGF-induced angiogenesis, endothelial cell proliferation, migration, survival, and vascular permeability by activating downstream signaling pathways including MAPK, PI3K-Akt, and PLCγ1 upon ligand binding.

Picture

FC

Flow cytometric analysis of bEnd.3 (Mouse brain endothelioma, Right) / NIH/3T3 (Mouse embryonic fibroblast, Left) cells labelling CD309 antibody at 1/200 dilution (1 μg)/ (Red) compared with a Rat monoclonal IgG (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Rat IgG PE was used as the secondary antibody.
Negative control: NIH/3T3