Flow cytometric analysis of C57BL/6 mouse thymocytes labelling Mouse CD198 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD4 - Brilliant Violet 421™ Antibody separately.
Rat Anti-Mouse CD198 Antibody (S-R626)
Rat Anti-Mouse CD198 Antibody (S-R626)
Price:
Regular price
$130.00 SGD
Regular price
Sale price
$130.00 SGD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | CD198 |
| Synonyms | C-C chemokine receptor type 8; C-C CKR-8; CC-CKR-8; CCR-8; CDw198; Cmkbr8; Ter1; Ccr8 |
| Location | Cell membrane |
| Accession | P56484 |
| Clone Number | S-R626 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse thymocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:200 | Ms |
Background
CD198, also known as C-C chemokine receptor type 8 (CCR8), is a 41 kD G protein-coupled receptor with seven transmembrane regions, belonging to the beta chemokine receptor family. It is expressed by various immune cells, including subsets of thymocytes, Tregs, NKT cells, Th2-polarized cells, macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 plays a role in mediating chemotaxis toward its ligands, such as CCL1 and CCL18, and is involved in the regulation of monocyte chemotaxis and thymic cell apoptosis. Additionally, CCR8 is associated with Th2 lymphocytes and has a role in allergic diseases. It is also considered an alternative coreceptor to CD4 for HIV-1 infection.
Picture
Picture
FC
