Flow cytometric analysis of BALB/c mouse bone marrow labelling Mouse CD138 antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Rat IgG2a, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD45R/B220 - Pacific Blue™ Antibody separately.
Rat Anti-Mouse CD138 Antibody (S-R514)
Rat Anti-Mouse CD138 Antibody (S-R514)
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Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | CD138 |
| Synonyms | Syndecan-1; SYND1; Synd-1; Sdc1 |
| Location | Secreted, Membrane |
| Accession | P18828 |
| Clone Number | S-R514 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse bone marrow |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Ms |
Background
CD138 (syndecan-1) is a type-I transmembrane heparan-sulfate/chondroitin-sulfate proteoglycan that tethers the cytoskeleton to the extracellular matrix, mediating adhesion, migration, and exosome biogenesis while acting as a co-receptor for growth factors and chemokines . It is constitutively expressed on epithelial cells and terminally differentiated plasma cells (making it a selective marker for plasma-cell neoplasms), but absent from mature B cells. Shed soluble CD138 is a prognostic indicator in multiple myeloma and other cancers; its overexpression or loss correlates with tumor progression, angiogenesis, and metastasis in solid tumors such as breast, colorectal, and liver cancers .
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