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Rabbit Anti-Mouse IL-2 Antibody (S-2117-6)

Rabbit Anti-Mouse IL-2 Antibody (S-2117-6)

Catalog Number: S0B5566 Application: ICFCM Reactivity: Mouse Conjugation: Unconjugated Brand: Starter
Price:
Regular price $110 USD
Regular price Sale price $110 USD
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Product Details

Product Specification


Host Rabbit
Antigen IL-2
Synonyms Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2
Immunogen Recombinant Protein
Location Secreted
Accession P04351
Clone Number S-2117-6
Antibody Type Recombinant mAb
Isotype IgG
Application ICFCM
Reactivity Ms
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
ICFCM 1:2000 Ms

Background

Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.

Picture

FC

Flow cytometric analysis of 4% PFA fixed 0.1% Tween-20 permeabilized C57BL/6 mouse splenocytes, Stimulated 6 hours with Stimulation Cocktail (Right panel) or untreated (Left panel) labelling Mouse IL-2 antibody at 1/2000 dilution (0.01 μg). Goat Anti - Rabbit IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD4 - Brilliant Violet 421™ antibody separately.

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