Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | PlGF |
| Synonyms | Placenta growth factor; PlGF; PGFL; PLGF; PGF |
| Immunogen | Recombinant Protein |
| Accession | P49763-2 |
| Clone Number | SDT-229-430 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against sFlt-1 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
PlGF, a key angiogenic protein, is primarily used in obstetrics to aid in the diagnosis and prediction of placental dysfunction-related conditions, particularly preeclampsia. Low PlGF levels (especially in the first and second trimesters) are strongly associated with impaired placental development, serving as a biomarker to differentiate preeclampsia from other hypertensive disorders. It also helps assess risks of fetal growth restriction and guides clinical decisions, enabling timely intervention and monitoring. Commercial assays (e.g., sFlt-1/PlGF ratio) enhance diagnostic accuracy and prognostic evaluation.
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