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PE Mouse Anti-Human CD25 (IL-2Rα) Antibody (7G7B6)

PE Mouse Anti-Human CD25 (IL-2Rα) Antibody (7G7B6)

Catalog Number: S0B81022 Application: FCM Reactivity: Hu Conjugation: PE Brand: Starter
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$110 USD
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Product Details

Product Specification


Host Mouse
Antigen CD25
Location Membrane
Accession P01589
Clone Number 7G7B6
Antibody Type Mouse mAb
Isotype IgG2a
Isotype Control S0B8530
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 0.1 mg/ml
Conjugation PE
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.09% sodium azide
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 2μl per million cells in 100μl volume Hu

Background

CD25, also known as IL2RA, is the alpha chain of the interleukin-2 receptor, a heterotrimeric protein complex that also includes beta (IL2RB) and the common gamma chain (IL2RG). It is a membranous glycoprotein primarily expressed on activated T lymphocytes and plays a crucial role in immune homeostasis by interacting with interleukin-2, a pleiotropic cytokine. CD25 is involved in the proliferation of T and B lymphocytes and is essential for the assembly of the high-affinity interleukin-2 receptor. In addition to its role in the immune system, CD25 is also expressed on certain non-immune cells and has been identified as a potential therapeutic target in cancers.

Picture

FC

Flow cytometric analysis of Human CD25 expression on Human PBMCs. Human PBMCs (peripheral blood mononuclear cells) were stained with Alexa Fluor® 647 Mouse Anti-Human CD4 Antibody and either PE Mouse IgG2a Isotype Control (left panel) or SDT PE Mouse Anti-Human CD25 Antibody (right panel) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.