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PD-L1 Recombinant Rabbit mAb (SDT-119-53)

PD-L1 Recombinant Rabbit mAb (SDT-119-53)

Catalog Number: S0B3586 Application: Sandwich ELISA Reactivity: Hu Conjugation: Unconjugated Brand: Starter
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$600 USD
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Product Details

Product Specification


Host Rabbit
Antigen PD-L1
Synonyms Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; hPD-L1; B7 homolog 1 (B7-H1); B7H1; PDCD1L1; PDCD1LG1; PDL1; CD274
Immunogen Recombinant Protein
Accession Q9NZQ7
Clone Number SDT-119-53
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against B7-H2, B7-H3, B7-H4, PD-L2, PD-1.
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

Soluble Programmed Death-Ligand 1 (sPD-L1) is found in the bloodstream and can be shed from the surface of tumor cells and immune cells. Elevated levels are primarily a marker of immune system suppression and are most significantly studied in the context of cancer. Serum PD-L1 serves as a valuable prognostic and monitoring biomarker in cancer, reflecting tumor-mediated immunosuppression. While promising for predicting outcomes and potentially guiding immunotherapy, it remains an investigational tool requiring further validation before widespread clinical adoption.

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