1μg (R: reducing condition, N: non-reducing condition).
NS1 His Tag protein, Dengue virus 2
NS1 His Tag protein, Dengue virus 2
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Product Details
Product Details
Product Specification
| Synonyms | DEN-2,Dengue NS1 protein,DENV2-NS1,Dengue virus (DENV) (type 2,strain New Guinea C) NS1 Protein |
| Accession | O92835 |
| Amino Acid Sequence | Asp776-Ala1127 with a polyhistidine tag at the N-terminus |
| Expression System | HEK293 |
| Molecular Weight | 45-50 kDa(Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Niranjan R, Sumitha MK, Sankari T, Muthukumaravel S, Jambulingam P. Nonstructural protein-1 (NS1) of dengue virus type-2 differentially stimulate expressions of matrix metalloproteinases in monocytes: protective effect of paracetamol. Int Immunopharmacol.2019 Aug;73:270-279. |
Background
Dengue virus (DENV) nonstructural protein 1 (NS1) is a 352-amino acid protein that exists in various oligomeric forms and is conserved within the flavivirus family. While extensively studied for its diagnostic potential, the role of NS1 in viral processes like replication and the development of clinical pathologies, including vascular leakage, remains incompletely understood. Many of these functions likely involve interactions with viral and host proteins that are yet to be fully elucidated.
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SDS-PAGE
SEC-HPLC
The purity of NS1 His Tag protein, Dengue virus 2 is greater than 95% as determined by SEC-HPLC.
